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KMID : 0371319950490040538
Journal of the Korean Surgical Society
1995 Volume.49 No. 4 p.538 ~ p.548
A Clinical Review in 19 Cases of Pheochromocytoma
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Abstract
In the 13-year period 1981~1994, nineteen patients with pheochromocytoma were reviewed at the Department of Surgery of Kyung Hee University Hospital. Bilateral adrenal tumors occured in one patient and extra-adrenal tumors occured in four
patients.
Fourteen patients had single tumors arising in one of the adrenal glands. The diagnosis and management of these patients are descrtibed. Hypertension was present in 89%(17/19), in which 47% appeared as persistent pattern and 42% as paroxysmal
pattern.
The urinary measurement of vanillylmandelic acid(VMA) was most sensitive and was increased in 94%(16/17) and plasma catecholamines were increased in 90%(9/10). The most useful localizing procedure was the computed tomography(CT) and the
meta-iodo-benzyl-guanidine (MIBG) scintigrphy. Operations were excisions for extra-adrenal tumors, unilateral total adrenalectomy for unilateral adrenal tumors, and unilateral total adrenalectomy and contralateral subtotal adrenalectomy for
bilateral
adrenal tumor. All tumors were confirmed as benign lesions because there were not direct invasion to adjacent structures and distant metastasis by gross and microscopic examinations. Of the 17 cases with hypertension, 88% was postoperatively
returned to
normotension.
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